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2025
| Paeonol attenuates oxidative stress and inflammation in experimental diabetic retinopathy by regulating the Nrf2/NF-κB signaling |
| Authors: Xiaoyu Li, Kehu Wu |
| General Physiology and Biophysics Vol.44, No.6, p. 529–538, 2025 |
| doi:10.4149/gpb_2025028 |
| Price: free access |
| [View Abstract] |
| DCAF1 promotes the growth and metastasis of pancreatic cancer cells by activating the PTEN/PI3K/Akt signaling pathway |
| Authors: Jiawei Wang, Yifeng Wu, Wenyi Xu, Qingqing Ruan |
| General Physiology and Biophysics Vol.44, No.6, p. 521–528, 2025 |
| doi:10.4149/gpb_2025037 |
| Price: free access |
| [View Abstract] |
| Role of SIRT1-HMGB1-NLRP3 inflammasome axis in the protective effects of trans-chalcone on myocardial ischemia and reperfusion injury |
| Authors: Xiuming Zhou, Juan Sun, Shouming Ren, Qifeng Shen, Qinghua Chi, Haijun Pang |
| General Physiology and Biophysics Vol.44, No.6, p. 509–519, 2025 |
| doi:10.4149/gpb_2025027 |
| Price: free access |
| [View Abstract] |
| LncRNA SOX2OT improves insulin resistance in type 2 diabetes with sleep disorders by activating IRS/PI3K/AKT and suppressing oxidative stress and inflammation through the miR-552-5p/SOX2 axis |
| Authors: Yalan Wang, Li Zheng, Jing Dai, Xiaoshi Yang, Feng Tang, Yan Li, Yu Lu |
| General Physiology and Biophysics Vol.44, No.6, p. 495–507, 2025 |
| doi:10.4149/gpb_2025035 |
| Price: free access |
| [View Abstract] |
| Transcription factor SPI1 exacerbates the malignant progression of esophageal squamous cell carcinoma byactivating LAMA3 expression |
| Authors: Juan Qin, Yunxiang Tang, Rui Zhu, Xuqin Feng, Jun Bie, Qikun Lv, Yang Shu |
| General Physiology and Biophysics Vol.44, No.6, p. 481–494, 2025 |
| doi:10.4149/gpb_2025029 |
| Price: free access |
| [View Abstract] |
| LncRNA SOX9-AS1 promotes the development of endometrial cancer by sponging miR-497-5p and upregulating E2F transcription factor 3 |
| Authors: Baojin Zeng, Jingjing Lin, Xiuling Ren, Yali Cheng |
| General Physiology and Biophysics Vol.44, No.6, p. 467–480, 2025 |
| doi:10.4149/gpb_2025016 |
| Price: free access |
| [View Abstract] |
| Saponin of Rhizoma Polygonati inhibits neuronal apoptosis and ameliorates cognitive deficits in Alzheimer’s disease mice by modulating c-Abl/MST1 pathway |
| Authors: Changying Zhang, Xudong Tang, Shixing Wu |
| General Physiology and Biophysics Vol.44, No.6, p. 451–465, 2025 |
| doi:10.4149/gpb_2025032 |
| Price: free access |
| [View Abstract] |
| Curcumin-chitosan microspheres inhibit epithelial cell PANoptosis: analysis of key PANoptosis gene distribution via single-cell RNA sequencing and in vivo validation in ulcerative colitis mice |
| Authors: Xinyou Pan, Qiaohong Zhu, Yanru Xiang, Jiaqi Liu, Chengdong Yu, Guodong Huang |
| General Physiology and Biophysics Vol.44, No.6, p. 439–450, 2025 |
| doi:10.4149/gpb_2025030 |
| Price: free access |
| [View Abstract] |
| Tripterygium glycosides alleviate CSE-induced lung injury by inhibiting IL-33 in bronchial epithelial cells |
| Authors: Nan Zhang, Jin Fan, Zhiping Deng |
| General Physiology and Biophysics Vol.44, No.5, p. 429–438, 2025 |
| doi:10.4149/gpb_2025026 |
| Price: free access |
| [View Abstract] |
| Biophysical study of calcium-containing DPPC liposomes prepared in water and a glycerol aqueous solution |
| Authors: Tamaz J. Mdzinarashvili, Mariam M. Khvedelidze, Salome V. Chinchaladze, Eka R. Shekiladze, Mariam T. Mdzinarashvili |
| General Physiology and Biophysics Vol.44, No.5, p. 419–427, 2025 |
| doi:10.4149/gpb_2025018 |
| Price: free access |
| [View Abstract] |
| WTAP regulates DDX3Y mRNA via m6A modification to promote high glucose-induced podocytes injury and diabetic nephropathy progression |
| Authors: Guanxi Li, Huijuan Zeng, Guojia Ru, Fang Yin, Siyi Liu, Jie He |
| General Physiology and Biophysics Vol.44, No.5, p. 405–417, 2025 |
| doi:10.4149/gpb_2025020 |
| Price: free access |
| [View Abstract] |
| circ_0049271 downregulation ameliorates lipopolysaccharide-induced human renal tubular endothelial cell apoptosis, inflammation and oxidative stress |
| Authors: Xiaozhen Ji, Jinjuan Zhang, Lefeng Zhang |
| General Physiology and Biophysics Vol.44, No.5, p. 391–403, 2025 |
| doi:10.4149/gpb_2025024 |
| Price: free access |
| [View Abstract] |
| Hypoxia-conditioned cardiomyocyte-derived exosomes attenuate myocardial injury via ANP-mediated M2 macrophage polarization |
| Authors: Mingye Wang, Chi Zhao, Tongtong Li, Tao Song, Yuanyuan Hao, Wenwen Cui, Min Guan, Yunlong Hou, Yang Li |
| General Physiology and Biophysics Vol.44, No.5, p. 377–389, 2025 |
| doi:10.4149/gpb_2025022 |
| Price: free access |
| [View Abstract] |
| Calycosin attenuates neuronal ferroptosis in Alzheimer’s disease mice by activating the Nrf2/HO-1 pathway |
| Authors: Qin Li, Bihua He, Ying Xiong |
| General Physiology and Biophysics Vol.44, No.5, p. 363–375, 2025 |
| doi:10.4149/gpb_2025021 |
| Price: free access |
| [View Abstract] |
| HuR enhances the stability of FGF19 mRNA to suppress Kupffer cell activation and mitigate inflammation and fibrosis in non-alcoholic fatty liver disease |
| Authors: XiaoQing Mo, SiJun Zhou, XiaoGe Zhou, Chun Huang |
| General Physiology and Biophysics Vol.44, No.5, p. 349–361, 2025 |
| doi:10.4149/gpb_2025023 |
| Price: free access |
| [View Abstract] |
| Exosomal microRNA-22-3p influences oxidative stress injury and neuronal apoptosis in Alzheimer’s disease via targeting KDM6B |
| Authors: Luzy Zhang |
| General Physiology and Biophysics Vol.44, No.4, p. 337–348, 2025 |
| doi:10.4149/gpb_2025009 |
| Price: free access |
| [View Abstract] |
| The regulatory role of Sigmar1 in CVB3-induced myocarditis |
| Authors: Fan Yang, Liqin Hu, Feng Pan, Xumei Chen, Xiaowen Lai, Xiaoqin Liu |
| General Physiology and Biophysics Vol.44, No.4, p. 327–336, 2025 |
| doi:10.4149/gpb_2025011 |
| Price: free access |
| [View Abstract] |
| Worenine enhances the sensitivity of non-small cell lung cancer A549/DDP cells to cisplatin via HIF-1α/BNIP3-mediated mitophagy |
| Authors: Guobiao Yang, Mengmin Xu, Mingliang Wu, Ya Zhang, Feiyan Yang |
| General Physiology and Biophysics Vol.44, No.4, p. 317–326, 2025 |
| doi:10.4149/gpb_2025012 |
| Price: free access |
| [View Abstract] |
| Protocatechuic acid alleviates chronic obstructive pulmonary disease model by reducing inflammation and oxidative stress via the AHR/CYP1A1/CYP1A2 pathway |
| Authors: Xingyu Pan, Xiaowei Zhang, Ruizhi Li, Sheng Zhang, Chengda Zhang, Yongjia Zhu |
| General Physiology and Biophysics Vol.44, No.4, p. 303–315, 2025 |
| doi:10.4149/gpb_2025013 |
| Price: free access |
| [View Abstract] |
| PSPH promotes colorectal cancer growth by triggering autophagy through AMPK-ULK1 activation and enhancing tumor immune evasion |
| Authors: Jiajia Guan, Jie Ji, Bisheng Sun, Jun Fu, Jie Luo, Bing Zhu |
| General Physiology and Biophysics Vol.44, No.4, p. 289–301, 2025 |
| doi:10.4149/gpb_2025019 |
| Price: free access |
| [View Abstract] |