Acta Virologica Vol.50, p.169-174, 2006

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Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

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Acta Virologica Vol.50, p.169-174, 2006
Title: FORMATION OF PSEUDORABIES VIRUS GLYCOPROTEIN E/I COMPLEX IN BACULOVIRUS RECOMBINANT SYSTEM
Author: J. TYBOROWSKA, N. RESZKA, G. KOCHAN, B. SZEWCZYK

Abstract: Glycoproteins E (gE) and I (gI) of Pseudorabies virus (PRV) form a non-covalently bound complex to which a number of functions have been attributed. The gE/gI complex formation was studied using a series of full-length and truncated forms of gE and gI expressed in baculovirus recombinant system. Both glycoproteins were truncated by stepwise removal of their C-terminal parts and their ability to form the complex was studied by radioimmunoprecipitation. It was found that N-terminal domains of gE and gI containing first 122 and 106 aa, respectively, were sufficient for the complex formation.

Keywords: baculovirus recombinants; envelope glycoproteins; gE/gI complex; Pseudorabies virus
Year: 2006, Volume: 50, Issue:	Page From: 169, Page To: 174


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