Acta Virologica Vol.52, No.1, p.23-30, 2008

Quarterly,
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

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Acta Virologica Vol.52, No.1, p.23-30, 2008
Title: THE UL31 TO UL35 GENE SEQUENCES OF DUCK ENTERITIS VIRUS CORRESPOND TO THEIR HOMOLOGS IN HERPES SIMPLEX VIRUS 1
Author: R. AN, H. LI, Z. HAN, Y. SHAO, S. LIU, X. KONG

Abstract: Five ORFs in the genome of Duck enteritis virus (DEV) corresponding to UL31, UL32, UL33, UL34, and UL35 genes of Herpes simplex virus 1 (HSV-1) were amplified by a modified “targeted gene walking” PCR, cloned, and sequenced. UL33, UL34, and UL35 genes were oriented from the left to the right of genome, while UL31 and UL32 had an opposite orientation. A comparison of deduced amino acid sequences of the DEV ORFs with their alphaherpesvirus homologs showed well-conserved regions except for the UL34 and UL35 genes. Phylogenetic analysis revealed that DEV was closer to the genus Mardivirus than to any other genus of the subfamily Alphaherpesvirinae. Based on this evidence, we proposed to assign DEV to the subfamily Alphaherpesvirinae.

Keywords: Duck enteritis virus; UL31, UL32, UL33, UL34, and UL35 gene sequences; phylogenetic analysis
Year: 2008, Volume: 52, Issue: 1	Page From: 23, Page To: 30


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