Home Endocrine Regulations 2006 Endocrine Regulations Vol.40, p.119-123, 2006

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Quarterly, 50 pp. per issue 
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

Published in English

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Endocrine Regulations Vol.40, p.119-123, 2006

Title: WEIGHT CHANGE AND ANDROGEN LEVELS DURING CONTRACEPTIVE TREATMENT OF WOMEN AFFECTED BY POLYCYSTIC OVARY
Author: J. VRBIKOVA, K. DVORAKOVA , M. HILL, L. STARKA

Abstract: Objective. The aim of this study was to investigate the effect of oral contraceptive Diane 35 (ethinylestradiol + cyproteroneacetate – EE/CPA) which is widely used in the treatment of PCOS in Europe, on body weight, lipid levels and endocrine parameters in non-obese women with PCOS. Subjects and methods. Nineteen PCOS women were examined in the early follicular phase of menstrual cycle, blood samples for the estimation of cholesterol (C), HDL cholesterol (HDL-C), triglycerides (TG), testosterone (T), androstenedione (A), dehydroepiandrosterone sulfate (DHEAS) and sex hormone binding globulin (SHBG) were taken before the start of treatment with Diane 35 and again after 7 ± 3.8 months of treatment with Diane 35. Body weight (W) was recorded at the time of both examinations. Results. After the treatment with Diane 35 the levels of W (p options for PCOS, besides contraception. Studies concerning body composition during contraceptive treatment in PCOS would be also useful in the future.

Keywords: Polycystic ovary syndrome – Cyproterone acetate – Androgen – Lipid levels – SHBG – Insulin resistance
Year: 2006, Volume: 40, Issue: 4 Page From: 119, Page To: 123



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