General Physiology and Biophysics Vol.26, p.240-242, 2007

Founded: 1982
ISSN 1338-4325 (online)
ISSN 0231-5882 (print)
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General Physiology and Biophysics Vol.26, p.240-242, 2007
Title: The effect of all-trans retinoic acid and/or colchicine on expression of rexinoid and thyroid hormone nuclear receptors and their coregulators in primary rat hepatocytes
Author: D. Macejova, Z. Dvorak, R. Vrzal, J. Ulrichova, S. Ondkova, J. Brtko

Abstract: In the present work, the effects of colchicine (COL) and/or all-trans retinoic acid (ATRA) on expression of rexinoid receptors (RXRs) (α, β, γ), thyroid hormone receptor α and coregulators N-CoR, SMRT and SRC-1 mRNA in primary rat hepatocytes as a model of no-proliferating cells were investigated. Treatment with these components, either alone or in combination, induced differences of the expression profiles between distinct treatment groups.

Keywords: Nuclear receptors — Transcription factors — Colchicine — ATRA
Year: 2007, Volume: 26, Issue:	Page From: 240, Page To: 242


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