Home HOME Neoplasma 2004 Neoplasma Vol.51, p.56-58, 2004

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

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Neoplasma Vol.51, p.56-58, 2004

Title: Effect of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in hairy cell leukemia
Author: K., DEDIC ; P., ZAK ;

Abstract: The study shows the influence of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in patients with hairy cell leukemia. Eighteen patients were studied; bone marrow fibrosis was graded 0-- 4 according to the quantity and pattern of distribution of reticulin. The grade of bone marrow fibrosis was established before the therapy and then in 12- and 24-month intervals. Patients showed complete remission after the therapy and remarkable reduction of bone marrow fibrosis.

Keywords: hairy cell leukemia, bone marrow fibrosis, 2- chlorodeoxyadenosine, 2-CdA, complete remission
Year: 2004, Volume: 51, Issue: Page From: 56, Page To: 58

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