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Neoplasma Vol.53, p.92-96, 2006 |
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| Title: Surfing on prothymosin alpha proliferation and anti-apoptotic properties | ||
| Author: K.P., LETSAS ; M., FRANGOU-LAZARIDIS ; | ||
| Abstract: Prothymosin alpha is an extremely abundant nuclear oncoprotein-
transcription factor essential for cell cycle progression and
proliferation that has been recently suggested as an anti-
apoptotic factor. Similarly to other oncoproteins, prothymosin alpha is
overexpressed in a variety of cancer tissues and cell lines. The
present review highlights on the proliferation and
anti-apoptotic properties of prothymosin alpha and its possible role
in cancer development.
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| Keywords: prothymosin alpha, transcription factor, proliferation, apoptosis, cancer | ||
| Year: 2006, Volume: 53, Issue: | Page From: 92, Page To: 96 | |
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