Home Neoplasma 2006 Neoplasma Vol.53, p.92-96, 2006

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6 times a year.
Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

Published in English

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Neoplasma Vol.53, p.92-96, 2006

Title: Surfing on prothymosin alpha proliferation and anti-apoptotic properties

Abstract: Prothymosin alpha is an extremely abundant nuclear oncoprotein- transcription factor essential for cell cycle progression and proliferation that has been recently suggested as an anti- apoptotic factor. Similarly to other oncoproteins, prothymosin alpha is overexpressed in a variety of cancer tissues and cell lines. The present review highlights on the proliferation and anti-apoptotic properties of prothymosin alpha and its possible role in cancer development.

Keywords: prothymosin alpha, transcription factor, proliferation, apoptosis, cancer
Year: 2006, Volume: 53, Issue: Page From: 92, Page To: 96

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