Home Neoplasma 2004 Neoplasma Vol.51, p.341-344, 2004

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

Published in English

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Neoplasma Vol.51, p.341-344, 2004

Title: Influence of diet containing lyophilized Enterococcus faecium M-74 with organic selenium on tumor incidence in Apc1638N mice
Author: K., HLUBINOVA ; B., RYCHLY ; V., ALTANEROVA ; L., EBRINGER ; C., ALTANER ;

Abstract: The aim of the present study was to test the effect of long-term application of diet containing Enterococcus faecium M-74 with organic selenium on tumor induction in transgenic mice carrying mutation in Apc gene. Heterozygosity for the Apc1638N mutation in mice causes development of small intestine and gastric tumors. Feeding of Apc1638N transgenic mice with enriched diet with probiotic components during 8 months have shown a minor therapeutic effect on the clinical manifestations in small intestine in comparison with control group.

Keywords: Apc gene mutation, transgenic mice, probiotic diet
Year: 2004, Volume: 51, Issue: Page From: 341, Page To: 344

Price: 9.60 €






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