Home HOME Neoplasma 2003 Neoplasma Vol.50, p.117-119, 2003

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

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Neoplasma Vol.50, p.117-119, 2003

Title: Usefulness of technetium-99m methoxyisobutylisonitrile liver single photon emission computed tomography to detect hepatocellular carcinoma
Author: Y.J., HO ; L.B, JEN ; M.D., YANG ; C.H., KAO ; C.C., LIN ; C.C., LEE ;

Abstract: Technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) has been shown to be useful in identifying several types of tumors, such as breast, lung and thyroid cancers. The usefulness of Tc-99m MIBI liver imaging in detecting hepatocellular carcinoma (HCC) is still controversial. In this study, 22 patients with HCC performed Tc-99m MIBI liver single photon emission computed tomography (SPECT). Twenty of 22 patients (90.9%) showed negative liver SPECT findings without significant Tc-99m MIBI uptake in HCC, and only 2 patients (9.1%) showed positive liver SPECT findings with significant Tc-99m MIBI uptake in HCC. In addition, no significant correlation between liver SPECT findings with sex, age, alpha feto-protein serum level, HCC differentiation, and virus hepatitis status was found. We concluded that Tc-99m MIBI liver SPECT is not a sensitive tool to detect HCC.

Keywords: Technetium-99m methoxyisobutylisonitrile, hepatocellular carcinoma, single photon emission computed tomography.
Year: 2003, Volume: 50, Issue: Page From: 117, Page To: 119

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