Acta Virologica Vol.49, p.129-132, 2005

Quarterly,
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

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Acta Virologica Vol.49, p.129-132, 2005
Title: GENOTYPING OF URUGUAYAN HUMAN ADENOVIRUS ISOLATES COLLECTED BETWEEN 1994 AND 1998
Author: S. FRABASILE, N. VITUREIRA, G. PEREZ, S. MATEOS, J. ARBIZA

Abstract: Adenoviruses are one of the most frequent causative agents of acute lower respiratory infections in infants and young children. Twenty-three adenovirus isolates from nasopharyngeal aspirates of children hospitalized for acute lower respiratory infections in Uruguay between 1994 and 1998 were studied by restriction enzyme analysis. The genomic analysis showed that 60.9% (n = 14) of isolates belonged to the species Human adenovirus C (HAdV-C) and 31.9% (n = 9) to the species Human adenovirus B (HAdV-B). Whereas some isolates could be classified according to the published profiles into genotype or genomic variant, others displayed migration patterns not allowing classification. Eight isolates (89%) of HAdV-B corresponded to the Ad7h genotype that has been associated with severe and fatal pneumonia and necrotizing bronchiolitis in children in South America. The isolates of HAdV-C showed a great variability in accordance with the data published earlier.

Keywords: human adenoviruses; genotyping; restriction analysis
Year: 2005, Volume: 49, Issue:	Page From: 129, Page To: 132


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