Acta Virologica Vol.54, No.1, p.49-54, 2010
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Title: Protein interaction matrix of Papaya ringspot virus type P based on a yeast two-hybrid system |
Author: W. T. Shen, M. Q. Wang, P. Yan, L. Gao, P. Zhou |
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Abstract: Comprehensive analysis of the interactions between 10 mature proteins of Papaya ringspot virus type P (PRSV-P) was carried out based on a yeast two-hybrid system assay (YTHS). We detected 6 interactions between different viral proteins (VPg-P1, VPg-P3, VPg-CI, VPg-CP, NIaPro-CI, and NIb-P3) and 4 self-interactions (HC-Pro, VPg, NIaPro, and CP). These interactions did not show the same directionality as corresponding interactions detected in other potyviruses and consequently, a protein interaction matrix displayed different patterns. This initial map of the protein interactions of PRSV-P allows further study of various viral proteins in order to develop a new strategy to control PRSV-P infection.
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Keywords: Potyvirus; protein-protein interaction; Papaya ringspot virus; yeast two-hybrid system |
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Year: 2010, Volume: 54, Issue: 1 |
Page From: 49, Page To: 54 |
doi:10.4149/av_2010_01_49
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Price:
14.40 €
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