Home HOME Acta Virologica 2010 Acta Virologica Vol.54, No.1, p.49-54, 2010

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Quarterly,
Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Impact Factor = 1.82

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Acta Virologica Vol.54, No.1, p.49-54, 2010

Title: Protein interaction matrix of Papaya ringspot virus type P based on a yeast two-hybrid system
Author: W. T. Shen, M. Q. Wang, P. Yan, L. Gao, P. Zhou

Abstract: Comprehensive analysis of the interactions between 10 mature proteins of Papaya ringspot virus type P (PRSV-P) was carried out based on a yeast two-hybrid system assay (YTHS). We detected 6 interactions between different viral proteins (VPg-P1, VPg-P3, VPg-CI, VPg-CP, NIaPro-CI, and NIb-P3) and 4 self-interactions (HC-Pro, VPg, NIaPro, and CP). These interactions did not show the same directionality as corresponding interactions detected in other potyviruses and consequently, a protein interaction matrix displayed different patterns. This initial map of the protein interactions of PRSV-P allows further study of various viral proteins in order to develop a new strategy to control PRSV-P infection.

Keywords: Potyvirus; protein-protein interaction; Papaya ringspot virus; yeast two-hybrid system
Year: 2010, Volume: 54, Issue: 1 Page From: 49, Page To: 54
doi:10.4149/av_2010_01_49
Price: 14.40 €






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