Home Acta Virologica 2010 Acta Virologica Vol.54, No.2, p.91-98, 2010

Journal info

Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Impact Factor = 1.82

Aims and Scope
Abstracted and Indexed

Select Journal

Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Acta Virologica Vol.54, No.2, p.91-98, 2010

Title: Analysis of Chinese Rabies virus isolates from 2003–2007 based on P and M protein genes
Author: S. Hirano, G. Sato, Y. Kobayashi, T. Itou, T. Rong_Luo, Q. Liu, N. Y. Jin, X. Xuan, T. Sakai

Abstract: Phylogenetic analysis of nucleotide sequences or deduced amino acid sequences of phosphoprotein (P protein), matrix (M) protein, and glycoprotein (G protein) genes of 18 Chinese isolates of Rabies virus (RABV) from 2003–2007 showed that these isolates formed a separate monophyletic lineage consisting of sub-lineages A and B. Compared with laboratory-fixed strains, recent Chinese isolates of sub-lineage B contained Val or Ala instead of Met69 in P protein, which is involved in generating truncated P proteins. In addition, one of these isolates CHpg3 had Pro instead of Ser63 and Leu instead of Ser64. Importantly, all functional domains of P and M proteins of all recent Chinese isolates were similar to those of laboratory-fixed strains. This study showed that although the recent Chinese RABV isolates belonged to a distinct lineage, their functional domains of P and M proteins were highly conserved.

Keywords: rabies virus; glycoprotein; phosphoprotein; matrix protein; China
Year: 2010, Volume: 2, Issue: 2 Page From: 91, Page To: 98
Price: 19.20 €

© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.