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General Physiology and Biophysics Vol.29, No.3, p.234–242, 2010
|Title: A possible role of NF-κB and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats|
|Author: Yoshitaka Ohno, Sumio Yamada, Takao Sugiura, Yoshinobu Ohira, Toshitada Yoshioka and Katsumasa Goto|
|Abstract: Effects of heat stress on phosphorylated nuclear factor-κB (phospho-NF-κB) and tumor necrosis factor α (TNFα) contents in skeletal muscles were studied. Male Wistar rats (7-week-old) were randomly assigned to control and heat-stressed groups. Rats in heat-stressed group were exposed to heat stress (42°C for 60 min) in an incubator without anesthesia. Soleus muscles were dissected and weighted 1, 3, and 7 days after the heat exposure. Significant increases in the wet weight and protein content of soleus were observed 7 days following the exposure (p play a part of a role in heat stress-associated muscle hypertrophy.
|Keywords: Heat shock protein — Nuclear factor-κB — Tumor necrosis factor α — Satellite cell — Muscle protein|
|Year: 2010, Volume: 29, Issue: 3||Page From: 234, Page To: 242|