Home Endocrine Regulations 2010 Endocrine Regulations Vol.44, No.3, p.101-107, 2010

Journal info

Quarterly, 50 pp. per issue 
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

Published in English

Aims and Scope
Editorial Info
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Endocrine Regulations Vol.44, No.3, p.101-107, 2010

Title: INTERRELATIONSHIP OF ENDOCRINE GLANDS UNDER THERMAL STRESS: EFFECT OF EXOGENOUS GLUCOCORTICOIDS ON MINERAL, ENZYME, THYROID HORMONE PROFILES AND PHAGOCYTOSIS INDEX OF INDIAN GOATS
Author: V. Sejian, R. S. Srivastava
Abstract: Objective. The purpose of the investigation was to examine the pineal-adrenal-thyroid-immune axis in female goats under short-term heat stress. The study was conducted to observe the influence of glucocorticoids on biochemical, endocrine profile and non-specific immune response in propranolol treated goats.
Methods. Melatonin and glucocorticoid secretions and several other endocrine and biochemical blood parameters reflecting the animals well being were determined over a one week period after goats had been exposed to 40°C and 60% relative humidity for 17 days. Chemical pinealectomy was achieved using propranolol followed by exogenous hydrocortisone treatment. This treatment continued from day 11 to day 17 of the study. Blood samples were drawn on day 10 to assess heat stress effect and twice daily after each treatment from day 11 to 17 to find the effect of hydrocortisone on various parameters studied.
Results. Thermal stress significantly (P ≤ 0.05) affected the levels of plasma calcium, ACP, ALP, T3, T4 and phagocytosis index. Chemical pinealectomy significantly (P ≤ 0.05) affected plasma levels of the parameters studied and these could be significantly (P ≤ 0.05) counteracted by administration of hydrocortisone to varying levels. Chemical pinealectomy aggravated thermal stress; although administration of hydrocortisone could ameliorate the condition.
Conclusions, The data generated from the study help us to understand the functional relationship between pineal, adrenal and immune system, and how this relationship modifies the biochemical, endocrine and non-specific immune response for the well being of the goats under thermal stress.
Keywords: Goat - Thermal stress – Propranolol – Hydrocortisone – Hormones - Enzymes phagocytosis index -
Year: 2010, Volume: 44, Issue: 3 Page From: 101, Page To: 107
doi:10.4149/endo_2010_03_101
Price: 14.00 €





© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.