Home FOR AUTHORS General Physiology and Biophysics 2011 General Physiology and Biophysics Vol.30, No.1, p.1–10, 2011

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Quarterly, 80 pp. per issue
Founded: 1982
ISSN  1338-4325 (online)

Published in English

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General Physiology and Biophysics Vol.30, No.1, p.1–10, 2011

Title: B cells – ontogenesis and immune memory development
Author: Zuzana Nescakova, Slavomir Bystricky

Abstract:  Functional diversity in the distinct developmental stages as well as anti-pathogen effectiveness and memory functionality make B cells unique and attractive object of physiology studies of the immune system. B cells are produced throughout the life of an organism, originate from the hematopoietic stem cells before birth and continue to differentiate to terminal stages. Over the past decade, there has been considerable progress in the research of all B cell intermediates and developmental processes. In this review, we will try to bring brief and comprehensive description of the current understanding of this fascinating topic.

Keywords: B lymphocytes — Germinal centre — Immunological memory — Memory B cells — Plasma cells
Year: 2011, Volume: 30, Issue: 1 Page From: 1, Page To: 10
doi:10.4149/gpb_2011_01_1


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