Home FOR AUTHORS General Physiology and Biophysics 2011 General Physiology and Biophysics Vol.30, No.4, p.356–363, 2011

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Founded: 1982
ISSN  1338-4325 (online)

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General Physiology and Biophysics Vol.30, No.4, p.356–363, 2011

Title: Evaluation of trace elements and oxidative stress levels in the liver and kidney of streptozotocin-induced experimental diabetic rat model
Author: Dervis Ozcelik, Matem Tuncdemir, Melek Ozturk, Hafize Uzun

Abstract: In this study, we aimed to investage the relationship among trace elements (Cu, Fe, Zn and Mg) on oxidative and anti-oxidative substances in liver and kidneys tissues in streptozotocin (STZ) diabetic rat model. The mean levels of Fe and Cu were found significantly higher in the liver and kidneys of the diabetic rats, in comparison to the control rats. On the other hand, the mean levels of Zn and Mg in the liver and kidneys of the diabetic rats were significantly lower than in the control rats.
The liver and kidneys malonaldehyde (MDA) levels of the experimental group were found to be higher than in the control group (p (GSH) levels in the liver tissue of STZ-induced diabetic rats were found to be lower in the experimental group than in the control group (p 

Keywords: Trace element — STZ-diabetic rat — Oxidative stress — Liver — Kidney
Year: 2011, Volume: 30, Issue: 4 Page From: 356, Page To: 363

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