General Physiology and Biophysics Vol.30, No.4, p.415

General Physiology and Biophysics Vol.30, No.4, p.415–421, 2011

Founded: 1982
ISSN 1338-4325 (online)
ISSN 0231-5882 (print)
Published in English,
6 times per year

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General Physiology and Biophysics Vol.30, No.4, p.415–421, 2011
Title: Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum
Author: Li Y. Chu, Jong H. Lee, Yun S. Nam, Yu J. Lee, Won-Hee Park, Byung-Cheon  Lee, Daejin  Kim, Yoon H. Chung, Ji H. Jeong

Abstract: We have investigated whether extremely low frequency magnetic field (ELF-MF) induces lipid peroxidation and reactive oxygen species in mouse cerebellum. After exposure to 60 Hz ELF-MF at 2.3 mT intensity for 3 hours, there was a significant increase in malondialdehyde level and hydroxyl radical. ELF-MF significantly induced concomitant increase in superoxide dismutase without alteration in glutathione peroxidase activity. While glutathione contents were not altered, ascorbic acid levels were significantly decreased by ELF-MF exposure. These results indicate that ELF-MF may induce oxidative stress in mouse cerebellum. However, the mechanism remains further to be characterized.

Keywords: Extremely low frequency magnetic field — Lipid peroxidation — Hydroxyl radical — Superoxide dismutase — Ascorbic acid

Year: 2011, Volume: 30, Issue: 4	Page From: 415, Page To: 421
doi:10.4149/gpb_2011_04_415
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