Home Bratislava Medical Journal 2012 Bratislava Medical Journal Vol.113, No.1, p.19-20, 2012

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.113, No.1, p.19-20, 2012

Title: The variant translocation of ABL1 Gene t(2;9)(q21;q34) in a childhood T-cell acute lymphoblastic leukemia
Author: M. Karkucak, T. Yakut, B. Baytan, T. Gulten, A. M. Gunes

Abstract: We present the case of the childhood ALL that was identified by the translocation of the ABL1 gene to the q21 band of chromosome 2 without t(9;22)(q34;q11) translocation. The observation of a poor clinical course of the case may contribute to explanation of the action of t(9;22)(q34;q11) translocation, of which poor prognostic action is known on ALL’s, in terms of ABL1 gene, independent of the BCR gene. On the other hand, the prognostic significance of this variant ABL1 translocation detection, which is very rarely observed, will cast a light on future cases (Tab. 1, Fig. 1, Ref. 11).

Keywords: ABL1 gene translocation, T cell ALL.
Published online: 13-Jan-2012
Year: 2012, Volume: 113, Issue: 1 Page From: 19, Page To: 20

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