Home Endocrine Regulations 2012 Endocrine Regulations Vol.46, No.1, p.31-36, 2012

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Quarterly, 50 pp. per issue 
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

Published in English

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Endocrine Regulations Vol.46, No.1, p.31-36, 2012

Title: A case report of a patient with hyperparathyroidism and presumed sellar/parasellar brown tumor
Author: H. M. Lando

Abstract: Objective. This is a report of an 18 year old black female patient with primary hyperparathyroidism and a sellar/parasellar brown tumor and unusual nonresponsiveness to 1,25 vitamin D administration post parathyroidectomy but responsiveness postoperatively to 25 vitamin D administration.
Method. Report the history, physical exam, laboratory, and radiological findings of the patient with a possible sellar/parasellar brown tumor and review the pertinent literature.
Results. Female patient presented with hyperparathyroidism and brown tumors of the ribs and sternum which have disappeared one and one-half years post parathyoidectomy with resolution of postoperative hypocalcemia. She was found, on magnetic resonance imaging (MRI), to have a 3.4 x 4.7 cm sellar mass which appeared to be a brown tumor as it has decreased over a twelve month period of normal calcium. Postoperatively, she had an unusual response to 1,25 vitamin D in that her calcium did not increase with massive doses (2 mcg) but with 25 vitamin D only.
Conclusions. A patient is reported with a probable sellar/parasellar brown tumor and hyperparathyroidism. After initial parathyroidectomy the sellar/parasellar brown tumor still persisted and did not respond to 1,25 vitamin D but did respond to 25 vitamin D administration.

Keywords: hyperparathyroidism, brown tumor, calcium, parathormone, pituitary
Year: 2012, Volume: 46, Issue: 1 Page From: 31, Page To: 36
doi:10.4149/endo_2012_01_31
Price: 12.00 €






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