Home HOME Acta Virologica 2012 Acta Virologica Vol.56, No.1, p.3-9, 2012

Journal info

Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

Published in English

Impact Factor = 1.82

Aims and Scope
Abstracted and Indexed

Select Journal

Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Acta Virologica Vol.56, No.1, p.3-9, 2012

Title: Mechanisms of suppression of interferon production by porcine reproductive and respiratory syndrome virus
Author: L. ZHU, Y. ZHOU, G. TONG

Abstract: The recently emerged porcine reproductive and respiratory syndrome virus (PRRSV) leads to one of the most economically significant infectious diseases of swine worldwide. The virus modulates the host innate and adaptive immunity to escape its immune response to facilitate the infection. Interferons (INFs) are principal antiviral cytokines, which represent components of the innate immunity and are regarded as a bridge between the innate and adaptive immunity. Currently, accumulating evidence indicates that the virus has developed various strategies to counteract the IFN production. Here, various mechanisms utilized by the virus to antagonize the IFN induction are reviewed.

Keywords: porcine reproductive and respiratory syndrome virus; interferon; nuclear factor-κB; interferon regulatory factor 3
Year: 2012, Volume: 56, Issue: 1 Page From: 3, Page To: 9
Price: 14.00 €

© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.