Home CONTACT Neoplasma 2012 Neoplasma Vol.59, No.4, p.393-397, 2012

Journal info


6 times a year.
Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

Published in English

Editorial Info
Abstracted and Indexed
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Neoplasma Vol.59, No.4, p.393-397, 2012

Title: Increased ischemia-modified albumin levels in patients with gastric cancer
Author: E. FIDAN, A. MENTESE, H. KAVGACI, A. OREM, S. FIDAN, A. UZUN, F. OZDEMIR, F. AYDIN

Abstract:

Reactive oxygen species (ROS) are found in the development stages of carcinogenesis.
Fifty two patients with gastric cancer and 35 controls were enrolled in this trial. IMA, MDA, Total Oxidant Status (TOS), Total Antioxidant Status (TAS) and Oxidative Stress Index (OSI) were evaluated.

There was a significant increase in IMA and MDA levels in the patient group (0.405±0.111, 0.271±0.066; p= 0.0001 and 0.207±0.251, 0.077±0.103; p= 0.004 respectively). TOS was also higher in the patient group but it was not statistically different.

TAS was statistically lower and there was significant difference in OSI (0.621±0.394, 0.996±0.37; p=0.0001 and 9.68±18.2, 2.9±3.85; p=0.001 respectively). The areas under receiver operating characteristics curves for the determination of gastric cancer were 0.842 for IMA and 0.708 for MDA.


Increased levels of IMA, MDA and oxidative stress index were detected and this condition is associated with the impairment of oxidant-antioxidant balance.



Keywords: ischemia modified albumin, gastric cancer, oxidative stress
Published online: 10-Apr-2012
Year: 2012, Volume: 59, Issue: 4 Page From: 393, Page To: 397
doi:10.4149/neo_2012_051


download file



© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.