Journal info
|
||
Select Journal
Journals
Bratislava Medical Journal Endocrine Regulations 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 General Physiology and Biophysics Neoplasma Acta Virologica Studia Psychologica Cardiology Letters Psychológia a patopsych. dieťaťa Kovove Materialy-Metallic Materials Slovenská hudbaWebshop Cart
Your Cart is currently empty.
Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.
Endocrine Regulations Vol.46, No.2, p.61-66, 2012 |
||
Title: Relationship between disease activity and serum levels of vitamin D and parathyroid hormone in rheumatoid arthritis | ||
Author: J. Moghimi, A. Sadeghi, M. Malek, R. Ghorbani | ||
Abstract: Objective. Measuring vitamin D and its regulating hormones in the serum might be an accurate method for assessment of rheumatoid arthritis (RA) activity. We tested the hypothesis that the serum levels of vitamin D and parathyroid hormone (PTH) are associated with the grade of disease activity in an unselected cohort of patients with RA. Methods. A total of 158 patients who met the American College of Rheumatology criteria for RA were examined and categorized as the patients with the active RA (n = 87) and silent RA (n = 71). Blood samples were obtained after at least eight-hour overnight fasting and the levels of 25-OH-vitamin D and PTH were measured. Results. The levels of the vitamin D in patients with active RA were significantly lower than in those with silent RA (49.38±38.21 versus 64.64±43.61 nmol/l; p = 0.022). The PTH serum level lower than the normal range (< 0.8 nmol/l) was statistically observed similar in the active RA group compared with another ones (10.3 % versus 4.2 %, p = 0.149). Serum levels of vitamin D and PTH were not influenced by patients’ gender and age as well as the duration of disease. Conclusion. Serum level of vitamin D was inversely related to RA activity and this relationship might be independent of PTH secretion or activity. |
||
Keywords: rheumatoid arthritis, vitamin D, parathormone | ||
Year: 2012, Volume: 46, Issue: 2 | Page From: 61, Page To: 66 | |
doi:10.4149/endo_2012_02_61 |
||
Price:
12.00 €
|
||
|
||