Bratislava Medical Journal Vol.113, No.10, p.610–611, 2012
|Title: Is there an association between serum 25-hydroxyvitamin d concentrations and disease activity in rheumatoid arthritis?|
|Author: T. Baykal, K. Senel, F. Alp, A. Erdal, M. Ugur|
Background: Recently, it has been recognized that vitamin D not only is important for calcium metabolism and maintenance of bone healthy, but also plays an important role in reducing risk of many chronic diseases including rheumatoid arthritis (RA), systemic lupus erythematosus, insulin-dependent diabetes mellitus, multiple sclerosis, several cancers, heart and infectious diseases. In RA, the role of vitamin D is undefined.
Results: The mean serum 25(OH)D levels were significantly decreased in RA patients compared to healthy controls (p < 0.01) and were associated with higher levels of parathyroid hormone.
Vitamin D deficiency (i.e. < 30 ng/ml) was found in 50 patients (90.9 %).
Serum levels of vitamin D lower than 20 ng/ml were found in 72 % of patients. We did not find the correlation between serum 25(OH)D levels and disease activity parameters.
|Keywords: rheumatoid arthritis, 25-hydroxyvitamin D, disease activity.|
|Year: 2012, Volume: 113, Issue: 10||Page From: 610, Page To: 611|