Home Bratislava Medical Journal 2012 Bratislava Medical Journal Vol.113, No.10, p.616–619, 2012

Journal info


 


Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345
 

Aims and Scope
Editorial Info
Submission Guidelines

Select Journal







Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Bratislava Medical Journal Vol.113, No.10, p.616–619, 2012

Title: Euglycemic state reduces the incidence of critical illness polyneuropathy and duration of ventilator dependency in medical intensive care unit
Author: H. Mikaeili, M. Yazdchi, F. Barazandeh, K. Ansarin

Abstract:

Objective: To examine the effect of euglycemic blood glucose control with normal insulin therapy on the incidence of critical illness polyneuropathy and duration of mechanical ventilation compared to that of conventional insulin therapy in a medical ICU.
Background: Despite the criticism over increased risk of hypoglycemia, the prevention of hyperglycemia through intensive insulin therapy has recently been confirmed to reduce the critical illness polyneuropathy (CIP).
Methods: In a single blind randomized clinical trial, forty adult patients admitted to the medical ICU were randomized to either euglycemic control (80–140 mg/dL) (Group N) or conventional approach (180–200 mg/dL, Group C). Duration of mechanical ventilation and the presence of CIP were investigated.

Results: The mean blood glucose levels were 131.76 ± 40.15 mg/dL in group N and 169.87 ± 50.66 mg/dL in group C (p < 0.001).

Patients in group N were on mechanical ventilation for significantly less time than those in group C (p = 0.04).

The diagnosis of CIP was significantly more frequent in group C than in group N (p = 0.01).


Conclusions: Glucose control at levels 80–140 mg/dL with normal insulin administration is likely to be associated with both reduced incidence of CIP and duration of ventilator dependency in medical ICU (Tab. 3, Ref. 24).



Keywords: blood glucose, insulin, euglycemic, critical illness polyneuropathy, ventilator, intensive care unit.
Year: 2012, Volume: 113, Issue: 10 Page From: 616, Page To: 619
doi:10.4149/BLL_2012_139
Price: 9.60 €






© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.