Home Bratislava Medical Journal 2013 Bratislava Medical Journal Vol.114, No.3, p.109-114, 2013

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2


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Bratislava Medical Journal Vol.114, No.3, p.109-114, 2013

Title: Advantages of isolated application of fibrin glue over suture in preservation of second-grade spleen lesion
Author: M. Jovanovic, N. Djordjevic, P. Djordjevic, Z. Damnjanovic, I. Smiljkovic, M. Radojkovic

Abstract: Objectives: The aim of this procedure was to assess the safety and efficiency of glue application in the treatment of lienal second-degree lesions, compared with traditional suture method of treatment.
Background: The spleen is the most frequently injured intra-abdominal structure regardless of injury mechanisms. Fibrin glue is a useful bio-adhesive for safe and efficient treatment of diffuse parenchymatous spleen haemorrhages.
Methods: Seventy dogs under intravenous anaesthesia were subdued to spleen incision in length of 5 cm and depth of 2 cm. Forty animals from the experimental group were treated with fibrin glue preservation, and 30 animals from the control group were treated with suture. Removed spleens were histologically analyzed. No animal was sacrificed.
Results: The application of fibrin glue allowed reparation to be accomplished in all cases. The effectiveness of primary repair was registered in 95 %, with only 5 % of cases requiring an application of fibrin omentoplasty. Secondary bleeding was registered only in 1 (2.5 %) case. Preservation with suture is primarily effective only in 40 %, requires additional repair in 23 %, and even 37 % of cases are not feasible. This method is characterized by mortality of 21 %, secondary haemorrhage (32 %), appearance of focal necrosis (42 %) and abscess (11 %).
Conclusions: Application of FG is a method of choice in cases of second-degree transcapsular spleen lesions and it has a considerable advantage over suture (Tab. 4, Fig. 6, Ref. 24).

Keywords: spleen injury, spleen preservation, fibrin glue, spleen suture.
Year: 2013, Volume: 114, Issue: 3 Page From: 109, Page To: 114

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