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Bratislava Medical Journal Vol.114, No.3, p.140-144, 2013 |
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Title: The immune status in situ of recurrent tonsillitis and idiopathic tonsillar hypertrophy | ||
Author: J. Semberova, B. Rychly, J. Hanzelova, J. Jakubikova | ||
Abstract: Objective: To analyze the immune status in situ of tonsils of patients with recurrent tonsillitis (RT) and idiopathic tonsillar hypertrophy (ITH) with the aim to discuss the indications of tonsillectomy (TE) and tonsillotomy (TT) in young children. The density of immunoglobulin IgG in the crypt epithelium in RT was significantly higher than in the ITH group (p = 0.041). We also measured a higher sera concentration of immunoglobulines (IgG, IgM, IgA) and TNF-α in RT compared to the ITH group (NS) and TH-1 immune response in tonsillar tissue based on differences between local cytokine concentration TNF-α and IL-4. |
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Keywords: recurrent tonsillitis, idiopathic tonsillar hypertrophy, immunohistochemistry, histology, immunity. | ||
Year: 2013, Volume: 114, Issue: 3 | Page From: 140, Page To: 144 | |
doi:10.4149/BLL_2013_031 |
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