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Bratislava Medical Journal Vol.114, No.4, p.189–191, 2013 |
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Title: Effect of iloprost on erythrocyte deformability in rat’s lower extremity undergoing an ischemia reperfusion injury | ||
Author: M. Arslan, T. Donmez, D. Erer, T. Tatar, F. M. Comu, M. Alkan | ||
Abstract: Aim: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. The protective effect of iloprost on local and distant organ injury due to I/R has been well documented but its effect on erythrocyte deformability needs further investigation. Our aim was to investigate the effect of iloprost on erythrocyte deformability in the infrarenal aorta of rats undergoing I/R. Conclusion: In our study, we detected the unfavourable effects of I/R on erythrocyte deformability, which may lead to disturbance in blood flow and hence tissue perfusion in the infrarenal rat aorta. We also found that Iloprost had beneficial effects by reversing the undesirable effects of I/R (Fig. 1, Ref. 15). |
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Keywords: erythrocyte deformability, ischemia reperfusion, ilioprost, rat | ||
Year: 2013, Volume: 114, Issue: 4 | Page From: 189, Page To: 191 | |
doi:10.4149/BLL_2013_040 |
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