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Bratislava Medical Journal 2013 Bratislava Medical Journal Vol.114, No.5, p.283-286, 2013
Bratislava Medical Journal 2013 Bratislava Medical Journal Vol.114, No.5, p.283-286, 2013
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Bratislava Medical Journal Vol.114, No.5, p.283-286, 2013 |
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| Title: The long-term response to treatment with calcium channel blockers in a patient with idiopathic pulmonary arterial hypertension. | ||
| Author: P. Solik, P. Lesny, M. Luknar, I. Varga, E. Goncalvesova | ||
| Abstract: Pulmonary arterial hypertension (PAH) is a disease characterised by a gradual increase in resistance of pulmonary circulation leading to right ventricular failure and death. In only 10 % of cases, there is a response to acute vasoreactivity testing with a significant reduction in mean pulmonary artery pressure (PAP), while in this group of patients, less than one half of cases benefit from long-term treatment with calcium channel blockers (CCB). This paper describes a case report of a young patient with dyspnoea and suspicion of pulmonary hypertension who was referred to a specialised centre. The complex evaluation of her clinical state led to confirmed diagnosis of idiopathic pulmonary arterial hypertension (IPAH). Because there was a positive response to vasoreactivity testing, the treatment for IPAH was initiated with a high dose of CCB. This treatment markedly improved her clinical state as well as echocardiographic and hemodynamic findings. In this study, the authors present a diagnostic algorithm in pulmonary hypertension and emphasise the role of CCB in treatment of PAH in carefully selected patients (Tab. 1, Fig. 5, Ref. 7). |
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| Keywords: pulmonary hypertension, pulmonary arterial hypertension, acute vasoreactivity testing, treatment, calcium channel blockers. | ||
| Year: 2013, Volume: 114, Issue: 5 | Page From: 283, Page To: 286 | |
| doi:10.4149/BLL_2013_059 |
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