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Bratislava Medical Journal Vol.114, No.8, p.425-430, 2013 |
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Title: Effect of intra-abdominal volume increment on lungs in hemorrhagic shock | ||
Author: D. Liu, H. Tan, L. Zhang, Z. Wang, H. Ge, W. Zhang, S. Sun, H. Xiao, X. Huang | ||
Abstract: Intra-abdominal hypertension (IAH) causes lung dysfunction in patients after hemorrhagic shock resuscitation. We performed intra-abdominal volume increment (IAVI) to IAH and studied its effect on pulmonary function. Methods: Eight minipigs established for IAH model by exsanquination until shock, incomplete blockage of portal vein and overload resuscitation were randomly divided into IAVI group (n=4) and sham-operated control group (n=4). Bladder pressure, arterial blood gas analysis and thoraco-abdominal computed tomography (CT) scans were measured. The minipigs were sacrificed 26 h after surgery, and lung samples were harvested for measuring the wet-to-dry weight ratio and hematoxylin–eosin staining. |
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Keywords: hemorrhagic shock, resuscitation, IAH, CT, intra-abdominal volume increment, lung, minipig. | ||
Year: 2013, Volume: 114, Issue: 8 | Page From: 425, Page To: 430 | |
doi:10.4149/BLL_2013_090 |
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