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Bratislava Medical Journal Vol.114, No.10, p.561-565, 2013 |
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Title: Does preoperative administration of allopurinol protect the lungs from ischemia–reperfusion injury occuring during cardiopulmonary bypass? | ||
Author: Z. I. Gormus, J. B. Celik, N. Ergene, N. Gormus, A. K. Baltaci | ||
Abstract: Background: It is investigated whether preoperative allopurinol administration protects lung injury induced by cardiopulmonary bypass (CPB).
TNF-alpha, IL-6, and IL-8 levels were lower in group A at T3, T4, T5 and T6 (p<0.05). Creatinin phosphokinase (CK) levels were lower in group A at T6 (p<0.05). CK-MB levels were lower in group A than in group C (p<0.05). Pulmonary function test (PFT) did not yield any differences between the groups. |
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Keywords: cardiopulmonary bypass, lung, ischemia-reperfusion injury, allopurinol. | ||
Year: 2013, Volume: 114, Issue: 10 | Page From: 561, Page To: 565 | |
doi:10.4149/BLL_2013_118 |
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