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Bratislava Medical Journal Vol.114, No.12, p.702-707, 2013 |
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Title: sTREM-1 in bronchoalveolar lavage fluid in patients with pulmonary sarcoidosis, effect of smoking and inflammation | ||
Author: M. Suchankova, M. Bucova, Tibenska E, J. Demian, I. Majer, H. Novosadova, E. Tedlova, V. Durmanova, E. Paulovicova | ||
Abstract: Soluble TREM-1 (sTREM-1; Triggering receptor expressed on myelocytes) is a new inflammatory marker indicating the intensity of myeloid cells activation and the presence of infection caused by extracellular bacteria and mould. Since all PS patients except one were non-smokers we compared non-smokers PS with non-smokers ILD patients and found four times higher levels of BALF sTREM-1 in PS patients (P = 0.001). We also recorded the effect of smoking, ILD smokers had higher sTREM-1 levels than non-smokers (P = 0.0019). Higher concentrations of sTREM-1 were detected in BALF of patients with lymphadenopathy and with elevated inflammatory markers in BALF. |
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Keywords: bronchoalveolar lavage fluid, inflammation, interstitial lung diseases, sarcoidosis, TREM-1. | ||
Year: 2013, Volume: 114, Issue: 12 | Page From: 702, Page To: 707 | |
doi:10.4149/BLL_2013_148 |
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