Home Bratislava Medical Journal 2014 Bratislava Medical Journal Vol.115, No.1, p.25-29, 2014

Journal info


Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


Aims and Scope
Editorial Info
Submission Guidelines

Select Journal

Webshop Cart

Your Cart is currently empty.

Info: Your browser does not accept cookies. To put products into your cart and purchase them you need to enable cookies.

Bratislava Medical Journal Vol.115, No.1, p.25-29, 2014

Title: Treatment efficiency of resistant hypertension in cardiologist’s office
Author: A. Dlesk, G. Kamensky, M. Stefanik, M. Kuzma, M. Pernicky


Background: The target values of blood pressure have not been achieved in our population of patients sufficiently. The most difficult is a control of patients with resistant hypertension. We do not have data about efficiency treatment of these patients today.
Objectives: The aim of our study was to assess current treatment status and by antihypertensive treatment modification we tried to reach an adequate blood pressure control.
Methods: Fifty two patients suffering from resistant hypertension 2–3 degree ESC/ESH with high cardiovascular risk have been observed. Reaching of the target blood pressure values was verified by 24-hour ambulatory blood pressure monitoring.

Results: The target blood pressure values were achieved in 50 % of patients during 18 months.

We noticed a statistically significant difference (p<0.001) in a decrease of casual and 24-hour ambulatory blood pressure in the group of controlled hypertensive patients in comparison with a group where blood pressure did not decrease sufficiently.

In case of 50 % patients, the target blood pressure values have not been reached in spite of more antihypertensive drugs and a higher dose.
Conclusion: Adequately and systematically controlled patients were treated less intensively in comparison with an inadequately controlled group. 24-hour blood pressure monitoring analysis confirmed correction of the patological diurnal rhythm mostly in adequate blood pressure controlled group. In this group, we have noticed a statistically significant decrease of blood urea and creatinin levels and albumin/creatinin ratio in urine. Resistant hypertension needs multi-faceted approach with consistent control of all comorbidities in a case of problematic blood pressure control (Tab. 6, Fig. 1, Ref. 21).

Keywords: chronotherapy, 24-hour ambulatory blood pressure monitoring, diurnal blood pressure profile.
Year: 2014, Volume: 115, Issue: 1 Page From: 25, Page To: 29

download file

© AEPress s.r.o
Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.