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Bratislava Medical Journal Vol.115, No.4, p.216-220, 2014 |
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Title: The detection of early myocardial changes in asymptomatic diabetic individuals by 99mTc – Myoview gated-SPET and heart rate variability measurement | ||
Author: M. Migra, M. Knazeje, M. Ochodnicky, F. Kovar, A. Lacko, M. Mokan | ||
Abstract: Aims: Incidence of early myocardial changes in asymptomatic diabetic individuals is not clearly documented. In the present study, we examined diabetic patients without a history of cardiovascular disease with negative treadmill test and no signs of systolic dysfunction for presence of cardiac autonomic neuropathy established by measurement of heart rate variability (HRV) and 99mTc - Myoview gated-SPET. Diastolic dysfunction was found in 10 % of T1DM and 11 % of T2DM patients by echocardiography, whereas none of the patients had systolic dysfunction. SPET confirmed hypoperfusion in 35 % T1DM (p=0.01) and in 60 % T2DM (p=0.001). Diagnosis of cardiac autonomic neuropathy based on Ewing´s testing and HRV examination was established in 60 % of T1DM patients (p=0.001) and 77 % of T2DM patients (p=0.001). In T1DM group, significant association was found between cardiac autonomic neuropathy (CAN) and frequency of hypoglycaemia (p=0.04). No such correlations were found in patients with T2DM. |
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Keywords: 99mTc - Myoview gated-SPET, HRV measurement, diabetic heart disease. | ||
Year: 2014, Volume: 115, Issue: 4 | Page From: 216, Page To: 220 | |
doi:10.4149/BLL_2014_045 |
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