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Bratislava Medical Journal Vol.115, No.5, p.253-255, 2014 |
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Title: The effects of propofol and memantine on erythrocyte deformability | ||
Author: Y. Unal, F. M. Comu, U. Emik, M. Alkan, H. K. Pampal, M. Arslan | ||
Abstract: Objective: Propofol is an intravenous general anesthetic with a primary hypnotic effect. Memantine is an NMDA receptor antagonist that has been shown to reverse changes in memory and synaptic plasticity in animal models. This study aims to investigates whether propofol and/or memantine has any effects on erythrocyte deformability. Results: Erythrocyte deformability was significantly higher in Groups P, M and PM when compared to the Group C (p = 0.007 and p = 0.001, p <0.0001, respectively); while the erythrocyte deformability indices were similar in groups P, M and PM.
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Keywords: propofol, memantine, erythrocyte deformability, rat. | ||
Year: 2014, Volume: 115, Issue: 5 | Page From: 253, Page To: 255 | |
doi:10.4149/BLL_2014_052 |
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