Home Bratislava Medical Journal 2014 Bratislava Medical Journal Vol.115, No.5, p.280-286, 2014

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.2


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Bratislava Medical Journal Vol.115, No.5, p.280-286, 2014

Title: Diagnostic and therapeutic strategiesfor resistant arterial hypertension – focus on countries with emerging economies
Author: A. K. Zhanatbekova, L. K. Karazhanova, A. M. Begalina, S. Filipova

Abstract: Arterial hypertensionis an important worldwide health problem. Its relevance relatesboth to the high incidence and prevalence in all adult communities and to the high risk of serious and potentially fatal cardiovascular events dueto hypertension. Resistant hypertension is defined as a blood pressure (BP) remaining above goal (>140/90 mm Hg) despite the use of at least 3 optimally dosed antihypertensive drugs from different classes, with one of the drugs being a diuretic. The exact prevalence of RH is unknown, but it is generally estimated at 10-20% of hypertensive patients. The aim of this review article is to address several important issues: (1) How to diagnose true RH ? (2) What is the optimal state-of-art management of RH in the light of the most recent scientific evidence and what is the role of various medical specialties in this process ? (3) Are there any country specific issues related to diagnosing and treating of RH in Kazakhstan and if so, how to tackle them ?
Long-lasting resistant hypertension increases by 50-80% the risk of major cardiovascular events (myocardial infarction, stroke) and end-organ damage. (heart failure, vascular dementia, chronic kidney disease). Adherence to well chosen therapy is the key factor in achieving blood pressure control and this must be based on adequate patient education and universal access to drug therapy. Thus, early recognition and appropriate management of RH must be among the top priorities of all public health initiatives to reduce the burden of cardiovascular diseases (Tab. 2, Fig. 1, Ref. 31)

Keywords: resistant arterial hypertension, diagnosis, treatment.
Published online: 19-May-2014
Year: 2014, Volume: 115, Issue: 5 Page From: 280, Page To: 286

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