Home CUSTOMERS Neoplasma 2014 Neoplasma Vol.61, No.5, p.491-504, 2014

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Founded: 1954
ISSN 0028-2685
ISSN 1338-4317 (online)

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Neoplasma Vol.61, No.5, p.491-504, 2014

Title: Diffuse large B-cell lymphoma: The history, current view and new perspectives
Author: P. FLODR, P. LATALOVA, M. TICHY, Z. KUBOVA, T. PAPAJIK, M. SVACHOVA, K. VRZALIKOVA, L. RADOVA, M. JAROSOVA, P. MURRAY

Abstract: The basic principles of lymphoma classification(s) in general have been widely evolving in a course of decades of years wiht the use of contemporary resources and recent cutting edges in hematooncology on a clinical, morphological and molecular level bring new possibilities not only in improvements of diagnostic and prognostic algorithms and also bear new opportunities in so called targeted and tailored strategies of lymphoma therapy. The pathogenesis and biologic behavior of lymphoproliferations and even lymphomas should be studied in a context of lymphocytic and (neoplastic) lymphoid stage and chronologic development. In a current more complex insight into lymphoproliferations we would like to describe huge heterogeneity of diffuse large B-cell lymphoma in relationship to mandatory WHO classification since 2008 and the next development of knowledge in this field with potential new influence on an advancement of both classification and therapy.

Keywords: lymphoma, diffuse large B-cell lymphoma, classification, review
Published online: 16-Jul-2014
Year: 2014, Volume: 61, Issue: 5 Page From: 491, Page To: 504
doi:10.4149/neo_2014_062


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