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Bratislava Medical Journal Vol.115, No.11, p.680-684, 2014 |
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Title: The protective effects of dexmedetomidine on hepatic ischemia reperfusion injury | ||
Author: A. Kucuk, F. Yaylak, A. Cavunt-Bayraktar, M. Tosun, M. Arslan, F. M. Comu, M. Kavutcu | ||
Abstract: Objective: The aim of this study was to evaluate the effect of dexmedetomidine (100 µg/kg-ip) on liver ischemia and reperfusion (I/R) in rats. Results: All parameters, except GST levels, were significant between the groups (p < 0.05). Although HSP60 expression was significantly increased between I/R, I/R-D and C groups there were no significant differences between I/R-D and C (p = 0.443). On the other hand, p53 expression was also significantly increased between I/R, I/R-D and C groups At the same time, there were no significant differences between I/R-D and C groups (p = 0.354). |
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Keywords: dexmedetomidine, ischemia reperfusion, HSP60, p53, rat. | ||
Year: 2014, Volume: 115, Issue: 11 | Page From: 680, Page To: 684 | |
doi:10.4149/BLL_2014_132 |
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