Home Endocrine Regulations 2014 Endocrine Regulations Vol.48, No.4, p.173-181, 2014

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Quarterly, 50 pp. per issue 
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

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Endocrine Regulations Vol.48, No.4, p.173-181, 2014

Title: Prognostic factors of survival and recurrence pattern in differentiated thyroid cancer: A retrospective study from Western Turkey
Author: V. Erol, O. Makay, G. Icoz, T. Kose, U. Yararbas, K. Kumanlioglu, M. Akyildiz

Abstract: Objectives. The aim of this study was to determine prognostic factors in patients with well-differentiated thyroid cancer (WDTC).
Methods. This retrospective study included 181 well-differentiated thyroid cancer patients who were operated between Decembers 1996-2007. Total of 181 patients [139 (76.8%) women and
42 (23.2%) men with a mean age of 46.3 years] who were subjected to a complete follow-up, were enrolled in the study. The mean follow-up period was 7.1 years (range 3.1 to 14.9 years). Medical records were reviewed regarding to age, gender, extent of surgery, tumor size, multifocality, clinical stage, capsule infiltration, extracapsular invasion, histological type, lymph node metastasis, distant metastasis, radioactive iodine treatment and prognosis.
Results. During follow-up, in 41 (22.6%) patients locoregional recurrences were detected and
5 (2.7%) patients passed away. Determined statistically significant prognostic factors were as follows; tumor size (histopathologically), extent of surgery, histological type, lymph node metastasis, tumor invasion (capsule and extracapsular) and clinical stage.
Conclusions. Well-differentiated thyroid cancer is a disease with good prognosis when detected early and appropriate treatment applied. Despite the prognosis, it is good to apply the right treatment and reduce recurrence and mortality rates, prognostic factors are well known and must be considered in patient management.

Keywords: thyroid cancer; prognostic factors; thyroidectomy
Year: 2014, Volume: 48, Issue: 4 Page From: 173, Page To: 181
Price: 18.00 €

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