Home Acta Virologica 2014 Acta Virologica Vol.58, No.4, p.356-358, 2014

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Founded: 1957
ISSN 0001-723X
E-ISSN 1336-2305

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Acta Virologica Vol.58, No.4, p.356-358, 2014

Title: Interleukin 8 enhances the immune response of ducks to avian influenza vaccine
Author: Y. RUAN, X. JI, M. WEN , X. ZHU, X. FU

Abstract: Interleukins are reported to be valuable immunostimulants in enhancing the immune efficiency of conventional vaccines. In this study, the effect of expression of interleukin 8 (IL-8) on the immune response of ducks to avian influenza vaccine was investigated. The results showed that the serum antibody titer, lymphocyte transformation efficiency and serum interferon gamma (IFN-γ) level of ducks injected with avian influenza vaccine along with a plasmid expressing duck IL-8 were higher than those of ducks injected with conventional immunostimulant Astragalus polysaccharide (APS) or empty plasmid. Therefore, the duck IL-8 may be used as a good immunostimulant to enhance the immune efficiency of avian influenza vaccine in ducks.

Keywords: interleukin 8; avian influenza virus; vaccine; Astragalus polasaccharide; duck; immune response
Year: 2014, Volume: 58, Issue: 4 Page From: 356, Page To: 358
doi:10.4149/av_2014_04_356


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