Endocrine Regulations Vol.49, No.1, p.11-19, 2015

Quarterly, 50 pp. per issue
Founded: 1967
ISSN 1210-0668
E-ISSN 1336-0329

Published in English

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Endocrine Regulations Vol.49, No.1, p.11-19, 2015
Title: Low vitamin D intake is associated with increase in cardiovascular risk factors in obese adolescents
Author: R. M. Campos, D. C. Masquio, F. C. Corgosinho, J. P. Carvalho-Ferreira, B. D. Netto, C. Ackel-D’Elia, L. Tock, S. Tufik, M. T. de Mello, A. R. Damaso

Abstract: Objectives. This study aimed to investigate the effect of vitamin D on cardiovascular risk in obese adolescents. Methods. Thirty (16 females/14 males) post-puberty obese adolescents (15-19 years) were involved and measurements of inflammatory biomarkers, body composition, visceral fat, and vitamin D (serum and intake) were performed. The adolescents were submitted to a long-term interdisciplinary therapy with physical exercise, nutritional, psychological, and clinical interventions. Results. Negative correlations between vitamin D intake with plasminogen activator inhibitor-1 (PAI-1) (r=-0.69; p=0.01) and vascular cell adhesion molecule (VCAM-1) (r=-0.82; p=0.001) were found in the population analyzed. Improvement in PAI-1, VCAM-1, body composition, and visceral fat, were observed. Conclusions. We showed that low vitamin D intake is associated with an increase in the cardiovascular risk factors in obese adolescents.

Keywords: vitamin D, obesity, adolescent, cardiovascular risk

Year: 2015, Volume: 49, Issue: 1	Page From: 11, Page To: 19
doi:10.4149/endo_2015_01_11
Price: 19.80 €

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