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Bratislava Medical Journal Vol.116, No.5, p.285-288, 2015 |
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Title: Perspective in predicting the effect of pleurodesis in the treatment of malignant pleural effusions | ||
Author: P. Habal, N. Omran, K. Kovacicova, J. Chek, K. Jankovicova, J. Mandak | ||
Abstract: Background: Pleurodesis with talc has been used for many years. No objective criteria of inflammatory symptoms are known in order to use them to predict the effect of therapy and selection of patients. A total of 114 patients were retrospectively divided into Group A (n1 = 98) of patients without relapse and Group B (n2 = 16) of patients with relapse of exudate. The need for repeated thoracic punctures or drainages over the course of a 12-month monitoring period was the criterion of treatment failure. Results: The groups were not different as for the baseline values of sTLR-2 (p0 = 0.638). Group A showed a marked growth during the monitoring period in 2 hours following talcage (p2 = 0.002) and in 24 hours (p24 = 0.016). Group B showed higher sCD-163 levels (p0 < 0.001). The initial sTREM-1 values and those after two hours were similar in both groups (p0 = 0.146; p2 < 0.0641). In 24 hours, Group A had markedly higher values (p24 < 0.001).
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Keywords: malign pleural exudate, thoracoscopy, talc, sCD163, sTLR2, sTREM1. | ||
Year: 2015, Volume: 116, Issue: 5 | Page From: 285, Page To: 288 | |
doi:10.4149/BLL_2015_054 |
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