Home FOR AUTHORS Bratislava Medical Journal 2015 Bratislava Medical Journal Vol.116, No.6, p.379-382, 2015

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.5

 

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Bratislava Medical Journal Vol.116, No.6, p.379-382, 2015

Title: The effect of polyethylene glycol adhesion barrier (Spray Gel) on preventing peritoneal adhesions
Author: F. Dasiran, R. Eryilmaz, A. Isik, I. Okan, A. Somay, M. Sahin
Abstract: The prominent cells in the late phase of wound healing during proliferation and matrix deposition are fibroblasts. Foreign materials in the operation site like prosthesis prolong the inflammation and induce fibroblast proliferation (8). 3 different prostheses used in this study induced chronic inflammation and fibrosis and provided an effective repair. Dense and thick adhesions due to fibrosis also induced strong adhesions to omentum and small intestine if only polypropylene mesh used for hernia repair. However, there was no difference between SprayGel treated polypropylene mesh and Sepramesh when compared for fibrosis. It also prevents the intraabdominal adhesion formation. It is nontoxic, sticky adherent, non- immigrant and easy to use both in open and laparoscopic surgeries. This experimental study revealed that polyethyleneglycol applied polypropylene mesh accomplishes hernia repair with significantly less adhesion formation than polypropylene mesh alone while securing a remarkable economy than adhesion barrier coated dual meshes (Tab. 6, Fig. 7, Ref. 23).
Keywords: abdominal surgery, adhesion, postoperative morbidity, hernia, barrier, wound healing, fibrosis.
Published online: 09-Jun-2015
Year: 2015, Volume: 116, Issue: 6 Page From: 379, Page To: 382
doi:10.4149/BLL_2015_072


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