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Bratislava Medical Journal Vol.116, No.9, p.554–559, 2015 |
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Title: Petroselinum crispum extract attenuates hepatic steatosis in rats fed with fructose enriched diet | ||
Author: V. Yuneesha Nair, N. Balakrishanan, J. Victor Antony Santiago | ||
Abstract: OBJECTIVE: This study was aimed to investigate the effects of addiction to nicotine and morphine and their withdrawal on coronary angiogenesis and serum NO concentrations in two-kidney one-clip hypertensive (2K1C) rats.
At the end of 8 weeks, the groups (2) were divided into the four sub-groups, which three of them were treated with withdrawal drugs. Following treatments, blood pressure, heart rate, plasma renin activity (PRA), NO concentration and capillary density were measured. Results showed that blood pressure was significantly reduced in the addicted group when compared to non-addicted (p < 0.05). The withdrawal completely reversed blood pressure to the level observed pre-addiction (p < 0.05). Coronary angiogenesis was significantly lower in the addicted group in comparistion to normal (p < 0.05) but withdrawal of addiction did not improve angiogenesis. |
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Keywords: Petroselinum crispum, non alcoholic fatty liver disease, non alcoholic steatohepatitis, lipid-hepatic function indicator. | ||
Published online: 28-Sep-2015 | ||
Year: 2015, Volume: 116, Issue: 9 | Page From: 554, Page To: 559 | |
doi:10.4149/BLL_2015_108 |
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