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Bratislava Medical Journal Vol.116, No.10, p.582–586, 2015 |
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Title: Reduced baroreflex sensitivity in patients with vasovagal syncope | ||
Author: P. Mitro, M. Simurda, L. Evin, P. Murin, E. Muller | ||
Abstract: OBJECTIVES: The evidence is conflicting regarding the role of baroreflex in patients with vasovagal syncope. The aim of the study was to measure baroreflex sensitivity (BRS) and hemodynamic parameters during head up tilt test (HUT) with nitroglycerine stimulation. RESULTS: HUT was positive after nitroglycerine administration in 28 patients and negative in 23 patients. BRS was lower at the time of syncope in HUT positive group compared to end-test values in HUT negative group (0.54±0.27 vs 0.72±0.35, p = 0. 03). At the time of syncope, CO was significantly lower in HUT positive patients compared to HUT negative patients (2.6±1.4 vs 4.3±1.4 l/min, p<0.0001), similarly as SV (34.7±14.7 vs 49.2±19 ml, p=0.005 ). LVET was significantly higher in syncopal patients (282.27±26.2 vs 240.5±58.8 ms, p=0.002) and TPR did not differ between two groups.
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Keywords: baroreflex, vasovagal syncope, head-up tilt test, hemodynamics. | ||
Published online: 28-Oct-2015 | ||
Year: 2015, Volume: 116, Issue: 10 | Page From: 582, Page To: 586 | |
doi:10.4149/BLL_2015_113 |
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