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Bratislava Medical Journal Vol.116, No.10, p.627–631, 2015 |
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Title: Iloprost and vitamin C attenuates acute myocardial injury induced by suprarenal aortic ischemia-reperfusion in rabbits | ||
Author: E. Iriz, A. Iriz, G. Take, H. Ozgul, L. Oktar, H. Demirtas, F. Helvacioglu, M. Arslan | ||
Abstract: OBJECTIVE: The aim of this study was to evaluate antioxidant and cytoprotective effects of iloprost and Vitamin C in a distant organ after abdominal aorta ischemia–reperfusion injury. Iloprost and iloprost + vitamin C groups significantly reduced the oxidative stress markers in tissue samples (p < 0.05) and significantly decreased the myofibrillar injury and mitochondrial morphology changes in the myocardial tissue as shown with electron microscopy (p < 0.05). Myocardial edema was significantly alleviated by iloprost and iloprost + vitamin C administration (p < 0.05). |
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Keywords: ischemia–reperfusion, remote, myocardium, iloprost, electron microscopy. | ||
Published online: 28-Oct-2015 | ||
Year: 2015, Volume: 116, Issue: 10 | Page From: 627, Page To: 631 | |
doi:10.4149/BLL_2015_121 |
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