Home General Physiology and Biophysics 2016 General Physiology and Biophysics Vol.35, No.1, p.71–75, 2016

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Founded: 1982
ISSN 1338-4325 (online)
ISSN 0231-5882 (print)
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General Physiology and Biophysics Vol.35, No.1, p.71–75, 2016

Title: The influence of zinc on the blood serum of cadmium-treated rats through the rheological properties
Author: Sherif A. A. Moussa, Abdulaziz Alaamer, Mohamed A. K. Abdelhalim

Abstract: The blood rheological properties serve as an important indicator for the early detection of many diseases. This study aimed to investigate the influence of zinc (Zn) on blood serum of cadmium (Cd) intoxication-treated male rats through the rheological properties. The rheological parameters were measured in serum of control, Cd, and Cd+Zn groups at wide range of shear rates (225–1875 s–1). The rat blood serum showed a non-significant change in cadmium-treated rats’ %torque and shear stress at the lower shear rates (200–600 s–1) while a significant increase was observed at the higher shear rates (650–1875 s–1) compared with the control. The rat blood serum viscosity increased significantly in the Cd-treated group at each shear rate compared with the control. The viscosity and shear rate exhibited a non-Newtonian behavior for all groups. The increase in blood serum viscosity in Cd-treated male rats might be attributed to destruction or changes in the non-clotting proteins, and other blood serum components. In Cd+Zn-treated rats, the rat blood serum viscosity values returned nearer to the control values at each shear rate. Our results confirmed that Zn displaced Cd or compete with the binding sites for Cd uptake.

Keywords: Rheological properties — Cadmium — Zinc — Viscosity — Rats
Published online: 15-Dec-2015
Year: 2016, Volume: 35, Issue: 1 Page From: 71, Page To: 75
doi:10.4149/gpb_2015030


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