Home Bratislava Medical Journal 2015 Bratislava Medical Journal Vol.116, No.12, p.741–745, 2015

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345
 

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Bratislava Medical Journal Vol.116, No.12, p.741–745, 2015

Title: Exercise training and detraining process affects plasma adiponectin level in healthy and spontaneously hypertensive rats
Author: O. Kilic-Erkek, M. Mergen-Dalyanoglu, E. Kilic-Toprak, S. Ozkan, M. Bor-Kucukatay, S. Turgut

Abstract: BACKGROUND: Adiponectin levels with long-term swimming exercise have been never investigated in spontaneously hypertensive rats (SHR).
OBJECTIVE: This study was aimed to investigate the effects of exercise and detraining process on the adiponectin plasma levels of spontaneously hypertensive rats (SHR) and healthy Wistar-Kyoto rats (WKY).
MATERIAL AND METHODS: The rats in the exercise groups were swimming for 10 weeks, 5 days/week, one hour in a day. The detraining rats were left to be sedentary in their cages for 5 weeks after 10 weeks of exercise period.
RESULTS: The plasma adiponectin levels decreased in E and SHRE groups compared to the SC and the SHR groups, respectively. In addition, blood pressure was decreased in the exercise groups vs their controls. The adiponectin level was not found to be significantly different in ED and SHRED groups compared to their controls. The blood pressure did not differ between SDC and ED groups, although in the SHRED group it was found to be lower than in SHRSD group rats.
CONCLUSION: The results of this study showed that exercise reduced plasma levels of adiponectin in healthy and spontaneously hypertensive rats. However, this difference disappeared at the end of the training processes. Our results suggest, that changes in plasma adiponectin levels are not responsible for changes in blood pressure (Tab. 2, Fig. 2, Ref. 43).

Keywords: adiponectin, spontaneously hypertensive rats (SHR, blood pressure.
Published online: 15-Dec-2015
Year: 2015, Volume: 116, Issue: 12 Page From: 741, Page To: 745
doi:10.4149/BLL_2015_145


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