Home Acta Virologica 2016 Acta Virologica Vol.60, No.1, p.55-61, 2016

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ISSN 0001-723X
E-ISSN 1336-2305

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Acta Virologica Vol.60, No.1, p.55-61, 2016

Title: The rate of co-infection for piglet diarrhea viruses in China and the genetic characterization of porcine epidemic diarrhea virus and porcine kobuvirus
Author: Z.-P. ZHAO, Z. YANG, W.-D. LIN, W.-Y. WANG, J. YANG, W.-J. JIN, A.-J. QIN

Abstract: Piglet diarrhea epidemics result in major economic losses for the swine industry. Four viruses are closely linked to porcine diarrhea: porcine kobuvirus (PKV), porcine epidemic diarrhea virus (PEDV), porcine transmissible gastroenteritis virus (TGEV), and porcine rotavirus (PRoV). We have conducted an epidemiology study to determine the frequency of infection and co-infection with these viruses in China, and characterized the genetic variation of the isolated PEDV and PKV strains. Stool and intestinal samples (n = 314) were collected from piglets with diarrhea in China from years 2012 to 2014. RT-PCR was used to detect PKV, PEDV, TGEV, and PRoV. Phylogenetic relationships between reference strains and the isolated PEDV and PKV strains were determined based on the M and 3D gene sequence. The rates of infection with PKV, PEDV, TGEV and PRoV were 29.9%, 24.2%, 1.91%, and 0.31%, respectively. Co-infections with PKV and the other three viruses were very common. Co-infection of PKV and PEDV was detected in 15.0% (47/314) of the samples. Phylogenetic analysis of the PKV 3D gene indicated that there were some phylogenetic differences in the PKV strains across regions within China. However, according to the PEDV M gene, strains clustered into three groups and the primary group was distinct from the vaccine strain CV777. This study provides insights in to the prevalence of diarrhea viruses and their prevention and control in China.


Keywords: porcine diarrhea viruses; co-infection; porcine kobuvirus; porcine epidemic diarrhea virus; porcine gastroenteritis; porcine rotavirus
Published online: 16-Mar-2016
Year: 2016, Volume: 60, Issue: 1 Page From: 55, Page To: 61
doi:10.4149/av_2016_01_55


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