Home Bratislava Medical Journal 2016 Bratislava Medical Journal Vol.117, No.5, p.251-253, 2016

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Published Monthly, in English
Founded: 1919
ISSN 0006-9248
(E)ISSN 1336-0345

Impact factor 1.564


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Bratislava Medical Journal Vol.117, No.5, p.251-253, 2016

Title: New data on harmful effects of trans-fatty acids
Author: E. Ginter, V. Simko

Abstract: Various margarines containing trans-fatty acids were marketed as being healthier because of the absence of cholesterol, suggesting to use margarine instead of butter. Fifteen years ago, research documented the grave health risk of trans-fats (T-fat). US FDA in 2015 finalized its decision that T-fat is not safe and set a three-year time limit for complete removal of T-fat from all foods. The greatest danger from T-fat lies in its capacity to distort the cell membranes. The primary health risk identified for T-fat consumption is an elevated risk of coronary heart disease. T-fats have an adverse effect on the brain and nervous system. T-fat from the diet is incorporated into brain cell membranes and alter the ability of neurons to communicate. This can diminish mental performance. Relationship between T-fat intake and depression risk was observed. There is growing evidence for a possible role of T-fat in the development of Alzheimer´s disease and cognitive decline with age (Fig. 1, Ref. 23).

Keywords: cis-fatty acids, trans-fatty acids, hydrogenated fat, plant oil, margarine, membranes, heart disease, cognitive defects, Alzheimer’s disease, food labeling
Published online: 13-May-2016
Year: 2016, Volume: 117, Issue: 5 Page From: 251, Page To: 253

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