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Bratislava Medical Journal Vol.117, No.6, p.358-362, 2016 |
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Title: Assessment of global ischemic/reperfusion and Tacrolimus administration on CA1 region of hippocampus: gene expression profiles of BAX and BCL2 genes | ||
Author: R. Badr, M. Hashemi, G. Javadi, A. Movafagh, R. Mahdian | ||
Abstract: BACKGROUND: It is well known that hippocampus has a pivotal role in learning, formation and consolidation of memory. Global cerebral ischemia causes severe damage to pyramidal neurons of the CA1 region and usually results in residual neurological deficits following a recovery from ischemia. Scientists investigate to find the molecular mechanism of apoptosis and to use this cell death for clinical treatment.
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Keywords: BAX, BCL2, ischemic/reperfusion, real-time RT-PCR, Tacrolimus | ||
Published online: 13-Jun-2016 | ||
Year: 2016, Volume: 117, Issue: 6 | Page From: 358, Page To: 362 | |
doi:10.4149/BLL_2016_071 |
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